Publications

Garge et al. 2026
Garge RK^, Lynch V, Fields R, et al. The proteomic landscape and temporal dynamics of mammalian gastruloid development. Nature Cell Biology (2026)
Pendyala et al. 2026
Pendyala S, Partington K, Bradley N, ..., Garge RK, et al. Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects. Cell (2026)
Fayer et al. 2025
Fayer S, Garge RK, Hopkins M, et al. Editing stem cell genomes at scale to measure variant effects in diverse cell and genetic contexts. medRxiv (2025)
Woo et al. 2025
Woo I, Casadei S, Snyder MW, ..., Garge RK, et al. Saturation genome editing of BARD1 resolves VUS and provides insight into BRCA1-BARD1 tumor suppression. medRxiv (2025)
Pinglay et al. 2025
Pinglay S, Lalanne JB, Daza RM, ..., Garge RK, et al. Multiplex generation and single-cell analysis of structural variants in mammalian genomes. Science (2025)
Hamazaki et al. 2024
Hamazaki N, Yang W, Kubo C, ..., Garge RK, et al. Induction and in silico staging of human gastruloids with neural tube, segmented somites & advanced cell types. Nature Cell Biology (2024)
Boyle et al. 2024
Boyle GE, Sitko K, Galloway JG, ..., Garge RK, et al. Deep mutational scanning of CYP2C19 reveals a substrate specificity-abundance tradeoff. Genetics (2024)
Garge et al. 2023
Garge RK, Geck RC, Armstrong JO, et al. Systematic Profiling of Ale Yeast Protein Dynamics across Fermentation and Repitching. G3: Genes, Genomes, Genetics (2023)
Abdullah et al. 2023
Abdullah M, Greco BM, Laurent JM, Garge RK, et al. Rapid, Scalable, and Combinatorial Genome Engineering by Markerless Enrichment and Recombination of Genetically Engineered Loci (MERGE) in Yeast. Cell Reports Methods (2023)
Bean et al. 2022
Bean BDM, Mulvihill CJ, Garge RK, et al. Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols. Nature Communications (2022)
Roberson et al. 2021
Roberson E, Battenhouse A, Garge RK, et al. Spatiotemporal transcriptomics of the cycling mouse oviduct. Developmental Biology (2021) [Cover]
Garge et al. 2021
Garge RK*, Cha HJ*, et al. Antifungal benzimidazoles disrupt vasculature by targeting one of nine β-tubulins. Genetics (2021) [Cover]
Garge et al. 2020
Garge RK, Laurent JM, Kachroo AH, Marcotte EM. Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes. Genetics (2020) [Cover]
Laurent et al. 2020
Laurent JM, Garge RK, Teufel AI, et al. Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs. PLoS Biology (2020)
Blank et al. 2020
Blank HM, Papoulas O, Maitra N, Garge RK, et al. Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveal coordinate control of lipid metabolism. Molecular Biology of the Cell (2020)
Akhmetov et al. 2018
Akhmetov A, Laurent JM, Gollihar J, ..., Garge RK, et al. Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9. Bio Protocol (2018)